The Best Hotel in St. Pauli and Schanzenviertel, Hamburg

The prime location between the Reeperbahn and the harbor, the clever use of space and light, and a top-floor cocktail joint, 20up, that attracts thousands every weekend make this a favorite with locals and out-of-towners alike. White-walled guest rooms feel spacious and airy, and most have river views. Dark-wood banquettes replace traditional desks, and pocket doors lead into the bright bathrooms. Even though the hotel is three short blocks from the center of the Reeperbahn, there is little noise.