Hotel Villa Hügel
This Art Nouveau villa dating from 1914 houses a family-run, full-service hotel that offers a nice mix of upscale and home-like atmosphere. With floor-to-ceiling windows in the excellent restaurant, and a rooftop terrace with infinity pool, there is no shortage of great views over the city. Other amenities include an indoor pool, sauna area, and—unusual for independent hotels in Germany—fully air-conditioned rooms. It's close to the amphitheater and Kaiserthermen and offers an excellent breakfast buffet.