2 Best Restaurants in Piazza Navona, Campo de' Fiori, and the Jewish Ghetto, Rome

Some of the most innovative interpretations of fine Roman cookery can be found in this starkly chic restaurant on a backstreet between upscale Via Giulia and the Campo de' Fiori. Chef Anthony Genovese was born in France to Calabrese parents and spent time cooking in Japan and Thailand, so his dishes make use of nontraditional spices, ingredients, and preparations—garnering him a loyal following and multiple accolades. The prices are exorbitant, but the food is exemplary. Dishes include pasta bundles filled with onion, tapioca, and red currant in a saffron broth or duck with black salsify, caramelized pear, and chocolate sauce. You can choose one of the elaborate tasting menus that range from 4 to 16 courses.

A gorgeous space, with chandeliers and soaring original brickwork ceilings, is the setting for one of Rome's best seafood restaurants. Order à la carte, or if you're hungry, the eight-course tasting menu (given the quality of the fish, a relative bargain at €90), which might include cuttlefish-ink tagliatelle with mint, artichokes, and roe or shrimp from the island of Ponza with rosemary, bitter herbs, and porcini mushrooms. There is a great wine list, as well as an extensive list of bottled waters for perfect pairings.