4 Best Hotels in Repubblica and Quirinale, Rome

This hotel near the glorious Santa Maria Maggiore Basilica is also close to Termini station, and has modern comforts and a great concierge—all at moderate rates. Stylish guest rooms have contemporary furnishings, bright red bedspreads and drapes, and soft lighting. The hotel's location is ideal if you want to be close to Termini without staying in a gritty part of town; there are also plenty of shops and restaurants nearby.

You'll feel right at home from the moment you waltz into this hotel in a 19th-century art nouveau building, where high ceilings, elegant chandeliers, white walls, and marble floors lend both elegance and warmth—all just a few blocks from Termini station. Guest rooms are tastefully decorated, mixing antique furniture and contemporary design; fresh flowers are displayed throughout the hotel and on the terrace. There are slightly formal lounges and a cozy bar on the third-floor terrace.

Just around the corner from Piazza della Repubblica, this extremely Instagrammable hotel has a lobby lounge with surrealist design elements, like lip-shaped sofas, and an interior courtyard done up in millennial pink. Guest rooms are a bit more subdued, with pastel fabrics, terrazzo floors, and Carrara marble bathrooms. After you've settled into your room, shimmy down to the bar, which is decked out in gold and mirrors with cloud-shaped hanging lamps.

You can do your sightseeing from the rooftop terrace of the Marcella, a midsize hotel with the feel of a smaller, more intimate establishment, where staff go the extra mile to make your stay pleasant. Many rooms also have good views, and all are decorated in tasteful color schemes, some with floral prints and mirrored walls. The spacious suites are ideal for families. The hotel is 10 minutes from Via Veneto and Termini Station.