9 Best Hotels in Villa Borghese, Piazza del Popolo, and Flaminio, Rome

Set in a 19th-century neoclassical palace, this cozy boutique hotel was remodeled to feature high-tech, elegant guest rooms while keeping the core structure, including unique windows and tall ceilings, intact. Spacious rooms feature plush blue velvet furniture, oak desks and bookcases, elegant marble bathrooms, and free Illy coffee. The two-Michelin-starred restaurant, Acquolina, serves innovative seafood dishes. The Acquaroof offers drinks and Mediterranean and Roman cuisine on the romantic top-floor terrace, with incredible 360-degree city views.

Established in 1925, this art deco--style hotel feels like an authentic time capsule of a more glamorous era. Exquisite wallpaper and fabric prints are coordinated in guest rooms, and some are decorated with antiques—the grandest suite has a red ceiling hand-painted in Venetian style. Everything is lovingly supervised by the owners. There's bar service on the panoramic roof garden and in the courtyard, and complimentary bicycles are available if you feel like braving the traffic. No wonder it's a favorite of filmmaker Wes Anderson, among other illustrious guests.

With a serene location near the Villa Borghese Gardens and a country-manor feel, this family-run art deco retreat attracts an older, well-off international crowd. The downstairs bar—a magnificent piece of cabinetry—is a conversation piece in itself. Upstairs, modern and antique styles combine to create highly polished opulence in guest rooms.

Just a quick walk from the Spanish Steps, this hotel has captured the hearts of many travelers over the years. Once a convent, this palazzo has seen it all, although now the decor is pure classic hotel decor, with a lot of polished surfaces, mirrors, and fine fabrics. There's also a piano bar, a restaurant with live music, and two panoramic rooftop restaurants, where you can relax after a busy day of sightseeing or retail therapy.

British brand The Hoxton's first foray into Italy is a design lover's dream filled with 1970s-inspired bespoke furniture, art tomes, and plants that transform the large lobby into intimate seating nooks perfect for socializing and coworking. The signature restaurant, Elio, serves delicious Italian cuisine, while Cugino offers pastries in the morning and creative Spritz cocktails with light bites in the evening. Rooms are modestly sized, with plush beds, Roberts stereos, flatscreen TVs, and free tea and coffee. Minibars have only water and milk, but guests can purchase snacks at the front desk. There's also a large event space called the Apartment, which can be rented out.

Once home to the Malaspina family who hosted high-society gatherings throughout the 18th century, this former Roman villa has public spaces that are sumptuously decorated with chandeliers, velvet curtains, and eclectic artwork. Rooms feature tasteful navy blue, taupe, or green details against white backdrops, with comfortable beds and minimal furniture. Some suites offer incredible details like beamed ceilings, terraces, design books, and prints by noted photographers. The gorgeous outdoor garden features olive and lemon trees, and a pool with sunbeds.

The 1960s-era facade of this large, seven-story hotel designed by Gio Ponti contrasts with the turn-of-the-20th-century Italian court decor and the extensive botanical garden outside, resulting in a combination of traditional elegance and contemporary pleasure. Windows in every room overlook an ocean of green, surmounted by St. Peter's dome. The hotel has wonderful indoor and outdoor swimming pools, a piano bar with stained glass and carved walnut appointments, a massive spa, and chamber music in the garden.

Set in a quiet residential neighborhood amid 15 acres of lush Mediterranean parkland, the Rome Cavalieri is a true hilltop oasis with magnificent views as well as three outdoor pools, one indoor pool, and a palatial spa. Rooms (ask for one facing the city) are spacious, with private balconies, striped damask, puffy armchairs, and no shortage of luxe amenities, including a pillow menu and luxurious bath products. The rooftop restaurant, La Pergola, is one of the best in the city.