10 Best Hotels in Siracusa and the Southeast, Sicily

On Ortigia's eastern shore, this hotel, in an unusual twist, is owned by Ursuline nuns, who help to make the mood placid and peaceful, but the accommodations are simple rather than monastic. Guest rooms are bright, modern, and decent for pricey Ortigia; some have sea views, while the others have balconies overlooking the street. There's also a slightly more expensive sister hotel, Domus Mariae Benessere, across the street, with a spa, pool, and fitness room that all guests can use.

Opened in 2024, the UNA group's stunning contemporary renovation of this lungomare limestone palazzo offers stylish public spaces and individual guest rooms, some with vibrant cassata-inspired pop art, others with antiquity-inspired mosaics. Stunning design delights you around every corner, from giant snails climbing an inner courtyard wall to space-age bathrooms with mood lighting and a tranquil, fragrant herb garden. 

Designed and run by charming Torino couple Cinzia and Dario, this stone-built former seminary turned chic, peaceful retreat near seaside Sampieri has rustic yet sophisticated rooms, panoramic terraces, and a gorgeous pool. The cozy social hub lounge/bar/dining area opens onto a large terrace with comfy loungers overlooking cacti- and olive tree-dotted gardens and pool, with the countryside and shimmering sea beyond.

With its own private farm, Tenuta Cammarana offers a full package of authentic Sicilian cooking, sumptuous accommodations, and a spa and pool on-site to relax in away from the sometimes packed streets of Ragusa. The rooms have been tastefully restored using painstakingly sourced furniture. Extra services like dinner, tours, and bespoke packages can be ordered in advance. The strategic location of Tenuta Cammarana means that it is equidistant from Ragusa and Modica, making it an ideal base for touring the area.

In a converted 18th-century palace on a quiet street behind Palazzo Ducezio, this smart hotel's main draw is its wonderful panoramic roof terrace bar, while offering less striking but nevertheless spacious, understated rooms. Though amenities are few, the public spaces make up for that: guests can enjoy breakfast outside in the charming garden. Noto's many restaurants and sights are just a few minutes away.

Winston Churchill, European royalty, and other VIPs have frequented the grand 18th-century Villa Politi, and although it's now a little faded, it retains a sense of elegance with rococo furnishings alongside basic modern luxuries like comfy beds. Set back from the road, the hotel is in the extensive gardens of the Latomie dei Cappuccini, overlooking a small archaeological site. Some rooms have balconies, private terraces, and partial sea views, others have far less salubrious views (be sure to check).

Since it's a bit off the beaten path, Scicli doesn't have too many hotels, but a good choice to rest your head is Albergo Diffuso, which can best be described as a “dispersed hotel,” where rooms are located in different historic homes throughout the town. The houses are all recently restored and well-equipped; and largely concentrated in a 1,000-foot radius of Via Francesco Mormina Penna.

Not far from Ragusa Superiore's cathedral, this smart hotel in a handsome 1700s-era stone palazzo has comfortable, spacious rooms with understated decor, a grand breakfast room with ornate ceiling, and a lovely garden with pool. Expect a curious and intriguing mix architectural styles, from grand noble saloni to rustic, stone-coved ceilings in the corridors. Unfortunately, while the building's unique historical features dazzle, the modern guest rooms can be slightly underwhelming.