5 Best Sights in Alcântara, Cais do Sodré, and Santos, Lisbon

A former industrial area that was transformed into a symbol of Lisbon's creative spirit, LxFactory is a colorful collection of cafés, bars, and boutiques. There's an excellent bookshop, Ler Devagar ("Read Slowly") with its own bar, plus a rooftop bar atop a hostel that serves cocktails to a young laid-back crowd. There's notable art to admire, too, and fans line up to snap pictures of the giant bee by Bordalo II, one of Lisbon's most celebrated street artists.

Portugal has a rich history of using puppets—from cute to creepy—to tell stories, and this fascinating museum is an opportunity to see the marionettes and masks up close. The only one of its kind in Portugal, the Marionette Museum has expanded in recent years to include an impressive collection of African and Asian puppets, and big-ticket visiting exhibitions have included a selection of puppets from Tim Burton's animated movies. The location, inside a former convent, adds an extra dash of drama to the proceedings, and there’s a chance to get hands-on with some of the puppets.

Portugal’s National Ancient Art Museum is housed in an opulent 17th-century palace, built at the behest of the Count of Alvor and later occupied by the brother of the Marquis de Pombal. Try not to spend too much time gaping at the dramatic painted ceilings, stucco detailing, and baroque doorways or you’ll miss the collection of more than 40,000 works, including the unsettling 1501 triptych Temptation of Saint Anthony by Hieronymus Bosch, one of the most important pieces in the country. A café set in lovely gardens is the perfect place for a bite.

Set inside an old factory complex (not to be confused with the much larger LxFactory), this is an open air cultural space hiding in plain sight on an unassuming side street. A discreet entrance leads to a highly Instagrammable spot filled with food trucks, bars, street art, and performance spaces.

A local landmark since 1892, the Mercado da Ribeira is worth a visit to see where locals go to buy some of the city’s freshest fruit, vegetables, fish, and seafood. The adjoining hall has become a bustling food court, Time Out Market. Some of Lisbon’s top chefs and most popular restaurants were invited to set up counter-service stalls with food to be enjoyed at communal seating areas. Although the clientele is predominantly tourists, it still offers a solid overview of local gastronomy.