13 Best Hotels in Palm Beach and the Treasure Coast, Florida

This stylish, contemporary boutique hotel in the heart of Vero's bustling Ocean Drive area has a gorgeous infinity pool overlooking the ocean and a distinctly Miami Beach vibe—just like its famous owners, singer Gloria Estefan and producer Emilio Estefan. The architecture features geometrical designs, apparent as you arrive at the impressive porte cochere entrance. Bold graphic prints decorate the common areas along with pieces of unique seagrass furniture woven in punchy, modern shapes. Rooms are sleek and filled with custom-made furnishings, teak paneling, and porthole windows. You get the feeling of being on a modern yacht with broad ocean views. Staff are friendly and accommodating. The Wave, the resort's restaurant, has become a favorite of locals, who come for the fresh seasonal menu and a DJ who spins on weekend nights.

Built in 1936, this romantic, two-story B&B is a short walk from Lake Worth's downtown shops, eateries, and the Intracoastal Waterway, and each room is decorated with antiques and inspired by a different artist, including Renoir, Dalí, Norman Rockwell, and Chagall. Three rooms and a suite are in the main building, and one suite and two rooms are across a brick courtyard in the carriage house. All rooms have oak floors, private balconies, and free Wi-Fi. There's an inviting parlor where you can relax with a good book; wine, soda, and water are always on offer. A full breakfast is served indoors or under the palms in the courtyard.

A classic antebellum-style hotel in the heart of town, the Clewiston Inn was built in 1938 to impress visiting businessmen and dignitaries; the cypress-paneled lobby, wood-burning fireplace, Colonial Dining Room, and Everglades Lounge with a wraparound Everglades mural are standouts. The 40 standard rooms, four suites, and eight efficiency apartments are furnished with pieces representative of the 1930s and 1940s with some more modern accents thrown in. Rates include a continental breakfast. There's a public pool across the street.

Not to be confused with the luxurious Colony in Palm Beach, this charming hotel in the heart of downtown Delray dates back to 1926, and although it's landlocked, it does have a cabana club 2 miles away for hotel guests only. The hotel is a member of the National Trust's Historic Hotels of America and maintains an air of the 1920s with its Mediterranean-revival architecture and retro Old Florida furnishings. The hotel's Cabaña Club, to which you are conveyed by shuttle, oversees a private stretch of beach and a heated saltwater pool. A convivial bar and live music on weekend nights make the lobby area a great place to wind down. Yoga classes are held there daily as well. Fine shops selling leather goods, body products, and stationery fill the lower-level storefronts.

This two-story hotel has one of the only swimming pools in the area, and it is on the rim canal that has a five-story observation tower for peeking over Lake Okeechobee's levee. Out back are a 650-foot fishing pier and The Boathouse, one of the lake area's best hangouts for shooting pool or watching TV, attracting a mix of locals and out-of-towners. You get a free drink ticket upon arrival. The best rooms are the suites, which are actually efficiency apartments with full kitchens.

This hotel is the best of the lodgings lining the scenic Fort Pierce Inlet on Seaway Drive (and that's not saying much); it's a practical base for fishing enthusiasts, with nice touches like two pools and a waterfront restaurant. Spacious, simply furnished units on two floors have kitchens or wet bars, and the staff puts fruit and Danish in the rooms each morning. Some rooms have a waterfront porch or balcony. A small cluster of apartments is across the street, away from the water and very quiet. Overnight boat docking is available for an additional $30 per night, and there's a sports outfitter at the marina with boat charters.

On the National Register of Historic Places, the two original buildings of this 1935 inn were built entirely from ocean-washed timbers with no blueprints; over time more buildings were added, and all are now decorated with such artifacts as ship's bells, Spanish tiles, a cannon from a 16th-century Spanish galleon, and plenty of wrought iron, which create a quirky, utterly charming landscape. The resort operates as both a time-share and a regular hotel (the website is just for informational purposes, so you must call to book rooms), and the complex has nine buildings on the beach with both modern and historic rooms and two swimming pools. It attracts guests from around the world, who sit in wooden rockers facing the beach, and extended-length stays are available. Waldo's restaurant and bar are on property, with several other choices across the street as well. Live music on weekends draws crowds to the pool.

It's a 15-minute walk to the beach from this B&B dating from 1915, set in a lushly landscaped, mango tree–dotted property. Each of the 11 rooms has a distinctive personality. The two ground-floor rooms have French doors opening onto a patio. A poolside cottage has two bedrooms and two bathrooms. Have your complimentary breakfast, which might include homemade raspberry buttermilk pancakes, on the veranda overlooking the heated pool or in the courtyard next to the fountain.

This cozy enclave on the banks of the Manatee Pocket with ocean access at the southern end of Stuart is the perfect place to set forth on a day at sea or wind down after one—it's relaxing and casual and has amenities like a swimming-pool courtyard, restaurant, and fitness center. The tropically furnished rooms are large and have balconies from which to enjoy the delightful waterfront views. The few suites include microwaves and refrigerators. There's a restaurant and a tiki bar by the water.

Right on the shore beneath the beautiful South Beach Park, this small, unpretentious resort was recently bought and renovated with a clean, modern decor. A few good restaurants are within walking distance, and it's a short drive to the plethora along Ocean Drive. The area by the beach is quite lovely, with a small pool, two shuffleboards, tiki huts for shade, and plenty of beach chairs.

A marina with deepwater slips—and a prime location at the mouth to the Atlantic Ocean on the Intracoastal Waterway across from Peanut Island—lures boaters and anglers here to these rather basic rooms, studios, and efficiencies. Each of the 30 rooms is named after an island in the Bahamas or a game fish, and all open onto the resort's landscaped grounds. Five are directly on the water, including a two-bedroom condo. Rooms have peaked ceilings, carpeting, flat-screen TVs, and stall showers; all have air-conditioning and ceiling fans. From the seawall, you'll see fish through the clear inlet water.

Built in the 1950s, this charming little motel-type lodge is conveniently located one block from South Beach on a quiet stretch of the causeway that goes to the mainland. The inn has pretty pastel paint, vintage artwork, and white wicker furniture. The plumbing and fixtures are mostly of the earlier era, and bathrooms are small, but you quickly look past them because all the studios and one bedrooms are spacious and have their own full kitchens and the nightly price is just right. In addition to being steps away from one of the widest and most beautiful beaches in the area, the hotel has a heated pool and a rooftop tiki sundeck and is a 2-mile bike ride from the Ocean Drive business district.

This historic Mediterranean-revival inn has lovely Old Florida original touches like cypress ceilings and pine floors. It's run by Jonnie Wall Flewelling, an Indiantown native whose family has owned the property for decades. Hunters, fishers, and birders are fans of this spot for its location, but it's got enough Southern charm to attract everyone—and the restaurant serves the finest fried-green tomatoes around. Carpeted rooms are done in country ruffles, and there are rocking chairs on the porch and a sitting area on the second floor. Indiantown memorabilia decorates the lobby, and there's good local art throughout, including a mural depicting the Seminole tribe's history.