Anchorage 1770
Sophisticated and full of charm, this stately home has soaring ceilings, four-poster rice beds, and views across the river, but skips all of the dusty antiques and knickknacks often common in family-run B&Bs. The owners, Frank and Amy, left behind business careers in Atlanta to renovate the mansion and convert it into a contemporary inn and restaurant, the Ribaut Social Club. It's a regular gathering place for locals, and a staple for frequent visitors.