16 Best Hotels in Piazza Navona, Campo de' Fiori, and the Jewish Ghetto, Rome

A cheerful hotel with irreverent art that overlooks Tiber Island, citizenM’s first Italian property has a young sensibility and is located close to Rome’s most ancient attractions. The modern rooms aren't exactly spacious, but they are smartly designed, comfortable, and ring in at reasonable rates while still offering a few frills like iPad controls and rainfall showers.

On a pedestrian-only street near the Pantheon, this lovely little hotel has an air of warmth and serenity, as well as a rooftop bar with great views of Rome. The exterior hasn't changed much since Stendhal stayed here in the 1800s; the interior, however, has been nicely restyled, with tasteful contemporary color schemes and furnishings, hardwood floors, and fully updated bathrooms.

Guests choose this hotel, run by members of the same family for 200 years, not only for its prime location, but also for its welcoming staff, top-notch service, and comfy beds. The decor is nothing to write home about: the lobby is an all-white affair with furniture you might find in your grandmother's house, and some rooms are a bit bland. For families or those looking for a bit more space, Santa Chiara has suites that can accommodate two to five people. Most, but not all, of the rooms and suites have small showers (and no bathtubs). If you'd like more room when you're scrubbing down, request on booking.

The granddaddy of Roman hotels and one of the oldest in the world—the doors first opened in 1467—this charming property is adjacent to the Pantheon and right in the middle of the lovely Piazza della Rotonda. Rooms are small but have been completely renovated and feature frescoes dating from the 17th century. Frederick III, Ariosto, Cagliostro, and Pietro Mascagni (celebrating the premier of his opera Cavalleria rusticana) all graced this hotel with their presence. If you would like a room overlooking the Pantheon, book directly through the hotel website.

The friendly sisters of Santa Brigida oversee simple, straightforward, and centrally located accommodations in one of Rome's loveliest convents, with a rooftop terrace overlooking Palazzo Farnese. You won't find iPhone charging docks or flat-screen TVs here, and breakfast is served only after the sisters have finished their morning prayer. Still, the atmosphere is serene, and the rooms are perfect for their rates. The Brigidine sisters, who wear a distinctive habit and veil with a caplike headband, are known for their gentle manner; they sometimes offer guests tickets to the papal audience. Breakfast is included, and you can elect to eat other meals (€25 per meal) here as well; however, your money might be better spent on meals elsewhere. The guesthouse entrance is around the corner from the church at Via di Monserrato 54.

In an old convent on Via Giulia, one of Rome's romantic ivy-covered streets, the D.O.M (Deo Optimo Maximo) is an ultrachic luxury hotel that resembles an aristocratic casa nobile. The interior design is cool and eclectic, with wood beam ceilings that date from the1600s, original Andy Warhol silkscreens, exposed brick walls, and scripture-inscribed marble slabs from the 15th century. The rooms, in warm neutral browns and grays, overlook the street. For real pampering, book the D.O.M Suite, which has a large terrace with views over typical Roman rooftops and bell towers. The real gem here, though, is the opulent but cozy bar and restaurant, VERVE, run by chef Adriano Magnoli and pastry chef Antonella Mascolo, where you can sit next to the fireplace during the winter or the stunning rooftop in the summer and enjoy some of the city's best cocktails.

With decor elements such as original wood-beamed ceilings, retro tiles, rich fabrics, contemporary art, and furniture that nods to 1930s and '40s Italian design, there's a hipster feel to this hotel inside a 17th-century palazzo around the corner from Piazza Navona. Top-floor rooms have little terraces where you can enjoy your morning cappuccino; other amenities include free Wi-Fi throughout the building, a coffee and tea maker in every room, and a ground-floor caffè and exhibition space that often promotes works by local artists. 

This friendly, comfortable, family-run hotel has relatively gentle rates for such a prime location---directly in front of the Pantheon. The rooms are all white with antique prints, hardwood floors, and contemporary furnishings.

This handsome, ivy-draped hotel is a romantic refuge in the heart of Campo de' Fiori. The hotel's colorful, elegant furnishings, frescoes, and exposed brick make it unique, as do the riveting views from the rooftop terrace. Cozy up to the fireplace in the hotel lobby, always crackling on cold nights and during the wintery months. In addition to the guest rooms, the hotel also offers apartments in the area that can accommodate two to five guests.

The edgy, of-the-moment design at this boutique hotel juxtaposes plush mid-century Italian furnishings with street art murals and industrial touches. On the ground floor, the contemporary fine dining restaurant and sleek bar are the place to unwind with a creative cocktail in hand. The Market caffè serves the kind of healthy salads and fresh juices that are rare in Rome. For summer sunsets, tables at the Mexican-themed Hey Güey rooftop terrace are in high demand.

This intimate boutique hotel from the team behind the Pierluigi restaurant is a top spot for wine lovers. The general manager is a sommelier, the wine cellar has 1,500 labels, each room comes with a personalized wine fridge, and the hotel organizes tastings with producers. Don't miss the complimentary aperitivo at Charade Bar, which has wallpaper illustrated by a local artist.

Just off the beautiful Piazza Navona, this aging but pleasant hotel has a lovely rooftop terrace that's the perfect place to enjoy a cappuccino or a glass of wine while taking in the view. Rooms are classically furnished, and the more updated ones have parquet floors and cheerfully striped wallpaper. You can snag a really good deal here in January and February, when room rates can go down to €130.

Situated in a remodeled Renaissance palazzo with one of the prettiest patio-courtyards in Rome, this hotel is a relaxing retreat close to Campo de' Fiori and Trastevere. Rooms have cherrywood accents, recessed lighting, and luminous marble floors. Some overlook the garden of the historic Palazzo Spada, and others offer a distant glimpse of the cupola of St. Peter's Basilica. Some suites have whirlpool tubs and balconies. The rooftop terrace is a great place to contemplate the city's skyline.

A member of Marriott's Autograph Collection, this boutique hotel is a sleek retreat in the center of the action. The design is clean lined and modern, with amenities like smart TVs, minibars stocked with full-size bottles of wine, and smartphones you can use while exploring the city. The Michelin-starred restaurant, Idylio by Apreda, serves creative cuisine by one of Rome's most renowned chefs, Francesco Apreda (formerly of the Hassler), and the Divinity Terrace on the rooftop offers a relaxing spot for an aperitivo (aperitif) surrounded by the church domes and terra-cotta roofs of Rome.

In a 15th-century palazzo on one of the city's oldest streets, Relais Giulia is a classic Roman Renaissance boutique hotel with sophisticated modern furnishings and fixtures. It's spread out over three floors and includes magnificently restored ancient frescoes, soaring original wood-beam ceilings and terra-cotta floors, flowing drapes, and romantic canopy beds. Amenities include whirlpool bathtubs, free Wi-Fi, iPads for guests to use at the reception, and flat-screen TVs.

This small hotel has reasonable rates considering its prime location—namely, a side street behind the lovely Via dei Coronari and right around the corner from Piazza Navona. The kitschy wallpaper prints wrapping the guest rooms are the notable cute factor in the otherwise standard lodgings.